2019/02/25 – Qiong Wu – Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions @SHB1021B

The molecular alterations that occur in cells before cancer is manifest are largely uncharted. Lung carcinoma in situ (CIS) lesions are the pre-invasive precursor to squamous cell carcinoma. Although microscopically identical, their future is in equipoise, with half progressing to invasive cancer and half regressing or remaining static. The cellular basis of this clinical observation […]