ProbRNA

Computational identification of protein binding sites on RNA using high-throughput RNA structure-probing data

 


Abstract

High-throughput sequencing has been used to probe RNA structures, by treating RNAs with reagents that preferentially cleave or mark certain nucleotides according to their local structures, followed by sequencing of the resulting fragments. The data produced contain valuable information for studying various RNA properties.

Results

We developed methods for statistically modeling these structure probing data, and extracting features potentially related to the tertiary structures of RNAs.

Materials

They have been moved to http://yiplab.cse.cuhk.edu.hk/probrna/

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